Authorized and Recommended Vaccines

Different COVID-19 Vaccines

The best COVID-19 vaccine is the first one that is available to you. Do not wait for a specific brand. All currently authorized and recommended COVID-19 vaccines:

are safe,

are effective, and

reduce your risk of severe illness.

CDC does not recommend one vaccine over another.

Pfizer-BioNTech

People 16 years and older
2 Shots Given 3 weeks (21 days apart)

Moderna

People 18 years and older
2 Shots Given 28 days apart

Johnson & Johnson Janssen

Persons 18 years and older
1 shot

Content provided and maintained by the US Centers for Disease Control and Prevention (CDC). Please see our system usage guidelines and disclaimer.


1 If you have had a severe allergic reaction (anaphylaxis) or an immediate allergic reaction to any ingredient in the vaccine you are scheduled to receive, you should not get that vaccine. If you have been instructed not to get one type of COVID-19 vaccine, you may still be able to get another type. Learn more information for people with allergies.

2 You should get your second shot as close to the recommended 3-week or 4-week interval as possible. However, your second shot may be given up to 6 weeks (42 days) after the first dose, if necessary.



Currently, three vaccines are authorized and recommended in the United States to prevent COVID-19:

Pfizer-BioNTech
Moderna
Johnson & Johnson / Janssen

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Vaccine Types

  • Understanding How COVID-19 Vaccines Work
    Learn how the body fights infection and how COVID-19 vaccines protect people by producing immunity. Also see the different types of COVID-19 vaccines that currently are available or are undergoing large-scale (Phase 3) clinical trials in the United States.​
  • COVID-19 mRNA Vaccines
    Information about mRNA vaccines generally and COVID-19 vaccines that use this new technology specifically.
  • Viral Vector COVID-19 Vaccines
    Information about viral vector vaccines generally and COVID-19 vaccines that use this new technology specifically.

Vaccines in Phase 3 Clinical Trials

As of February 27, 2021, large-scale (Phase 3) clinical trials are in progress or being planned for two COVID-19 vaccines in the United States:

AstraZeneca COVID-19 vaccine

Novavax COVID-19 vaccine​

Learn more about U.S. COVID-19 vaccine clinical trials, including vaccines in earlier stages of development, by visiting clinicaltrials.govexternal icon.

This page will be updated as additional information is available.Content provided and maintained by the US Centers for Disease Control and Prevention (CDC). Please see our system usage guidelines and disclaimer.

More Vaccine Information from CDC